Friday 18 September 2009

Placebos, Nocebos, and why you've got to believe

Most everyone has heard of the placebo effect. Essentially, if a doctor gives you a sugar pill and says it's going to make you feel better, you'll end up feeling a bit better, even though the pill did nothing at all. When you think your body is going to get better, you're likely to get better. In recent years, the placebo effect has actually been getting stronger, to the extent that even a few old standby drugs, like Prozac, will sometimes fail to prove their effects are statistically significant. (A really cool article on how the placebo effect is getting stronger is here.)

The placebo effect has a lesser known, decidedly evil cousin: the nocebo effect. The nocebo effect is just what it sounds like. When you're told something won't work, it won't work. If you're told you're going to die, and you believe it, you might even die. Scary stuff.

Those of you who read my blog know that I'm pretty damn into science, math, and reason. So I say this not in a bullshit pseudoscience The Secret sort of way.

You've got to believe.

You have to do this, too, all the working out and the hunger and the drinking water and building up calorie deficits day after day. But you have to believe you're doing it too. Believe what you're doing will work, and it seems that, on the margins, it's more likely to.

For reasons science hasn't yet figured out, people who genuinely believe they're going to get better are more likely to do so, and people who believe they won't get better sometimes end up doing just that. So go ahead, drink the koolaid, and tell yourself you are going to lose the weight. It's not going to be quite as effective as a guy in a white coat telling you his sugar pill will cure what ails you, but it very well might end up helping out.

You can do this. I can do this, too. And you know what? I think we both will.

And in other news, yesterday I started wearing my size 18 pants as my standard work pair. The size 20s we're just too big. I'm wearing them again today and they feel great. As someone who spends most of my time these days in oversized clothes, getting to wear a pair that really fits is a nice treat.

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